Kidney Function
Creatinine, eGFR, and BUN: key kidney markers.
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Biomarkers Included
3 biomarkersThis test measures three markers that reflect kidney function: creatinine, eGFR, and urea (BUN). Together, they can provide a snapshot of how well your kidneys are filtering waste products from your blood.
Why this test?
Your kidneys filter waste, regulate fluid balance, and help maintain blood pressure. Changes in kidney function often develop silently, without noticeable symptoms in the early stages. This panel measures creatinine, eGFR, and urea to give you direct data on your kidney performance.
Who is this test for?
This test may be relevant for:
- Men who follow a high-protein diet and want to check their kidney markers
- Those with a family history of kidney-related conditions
- Men using supplements such as creatine who want to monitor kidney function
- Anyone who wants baseline data on kidney health
What is tested?
- Creatinine (umol/l): a waste product from muscle metabolism; the kidneys normally filter it out efficiently
- eGFR (ml/min): an estimated glomerular filtration rate that indicates how well the kidneys are filtering blood
- Urea (BUN) (mmol/l): a byproduct of protein metabolism; elevated levels may suggest the kidneys are not clearing waste as effectively
What can this test tell you?
Creatinine and eGFR work together: elevated creatinine with a lower eGFR may suggest reduced kidney filtration capacity. Urea adds another layer of information, as it reflects both kidney function and protein intake. By evaluating all three markers, you get a more reliable picture than any single value could provide. Deviations may have various causes and do not automatically indicate a problem.
How is the sample collected?
A blood sample is drawn at a certified sample point (afnamepunt). There are over 750 locations throughout the Netherlands. The procedure takes approximately 10 to 15 minutes.
When is this test useful?
This test may be useful if you follow a high-protein diet, use creatine supplements, have a family history of kidney issues, or simply want to establish baseline values. It can also be relevant if you experience symptoms like changes in urination patterns, unexplained swelling, or persistent fatigue.
What do the results mean?
Your results will show whether each marker falls within the reference range. An elevated creatinine or urea, or a lower-than-expected eGFR, may warrant further investigation. However, factors such as muscle mass, hydration, and diet can influence these values. A healthcare provider can help you interpret the results in the context of your personal health profile.
What happens after the results?
Your results are typically available within a few business days. You will receive a clear report showing each marker and its reference range. Consider reviewing your results with a healthcare provider who can provide personalized context and guidance.
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Choose your blood test
Pick a testosterone check, hormone panel, or prostate screening. Or build a custom test with exactly the markers you want.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician assesses your results and writes a personal report. On your dashboard within a few business days.
Choose your blood test
Pick a testosterone check, hormone panel, or prostate screening. Or build a custom test with exactly the markers you want.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician assesses your results and writes a personal report. On your dashboard within a few business days.
Always a location near you
With more than 650+ certified phlebotomy points across the Netherlands.
What We Test
This panel includes 3 biomarkers, each tested at a certified laboratory using medical-grade equipment.
BUN (blood urea nitrogen) measures the amount of urea nitrogen in your blood, a waste product formed when the body breaks down protein. It is primarily used to evaluate kidney function and can be influenced by diet, hydration status, and liver health.
Learn moreCreatinine is a waste product generated by normal muscle metabolism that is filtered out of the blood by the kidneys. It is widely regarded as the gold standard marker for evaluating kidney function, as consistent production makes it a reliable indicator of filtration efficiency.
Learn moreeGFR (estimated glomerular filtration rate) is a calculated measure of how effectively your kidneys filter waste from the blood. It is the gold standard for diagnosing and staging chronic kidney disease and is derived from blood creatinine or cystatin C levels along with demographic factors.
Learn moreUrea (BUN)
KidneyBUN (blood urea nitrogen) measures the amount of urea nitrogen in your blood, a waste product formed when the body breaks down protein. It is primarily used to evaluate kidney function and can be influenced by diet, hydration status, and liver health.
BUN is a valuable marker for assessing how effectively your kidneys are filtering waste from your blood. Elevated levels may indicate that the kidneys are not functioning optimally, which can be associated with dehydration, kidney disease, or other underlying conditions. Monitoring BUN alongside other kidney markers such as creatinine and eGFR provides a more comprehensive picture of renal health and helps detect potential problems early.
Creatinine
KidneyCreatinine is a waste product generated by normal muscle metabolism that is filtered out of the blood by the kidneys. It is widely regarded as the gold standard marker for evaluating kidney function, as consistent production makes it a reliable indicator of filtration efficiency.
Creatinine is central to assessing kidney health. It is used to calculate the estimated glomerular filtration rate (eGFR), which is the primary measure for staging chronic kidney disease. Early detection of rising creatinine levels can prompt timely intervention, helping to slow the progression of kidney damage. Monitoring creatinine is also important for adjusting medication dosages, as many drugs are cleared by the kidneys.
eGFR (Estimated Glomerular Filtration Rate)
KidneyeGFR (estimated glomerular filtration rate) is a calculated measure of how effectively your kidneys filter waste from the blood. It is the gold standard for diagnosing and staging chronic kidney disease and is derived from blood creatinine or cystatin C levels along with demographic factors.
eGFR is the most important single measure for assessing overall kidney function. It is used internationally to diagnose chronic kidney disease, determine its stage, and guide treatment decisions. Regular eGFR monitoring allows early detection of kidney function decline, often before symptoms appear. This is critical because early intervention can significantly slow the progression of kidney disease and reduce the risk of complications such as cardiovascular disease.
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