Order an SHBG test alongside your testosterone
Measure your SHBG, the protein that binds your testosterone. Read together with testosterone it shows your hormone balance. No referral needed.
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Biomarkers Included
1 biomarkersSHBG stands for sex hormone-binding globulin, a protein made by your liver. It binds sex hormones in your blood, especially testosterone, and so helps determine how much testosterone is freely available to your body.
This test measures your SHBG in a blood sample taken at a certified sample point. You order online, need no referral and receive your results within a few working days, including a doctor's assessment.
Why this test?
SHBG on its own often says little. The test only becomes truly meaningful alongside a testosterone test, because your SHBG value shows how much of your testosterone is bound and how much stays free.
The measurement gives you a snapshot of a single protein, not a diagnosis. It is a data point you can discuss with a doctor alongside your testosterone and your symptoms.
For many men, this is a concrete first step towards understanding questions about energy, libido or recovery.
Who is this test for?
This test may suit men who:
- want to understand their testosterone better and see how much of it is usable
- experience symptoms such as low energy, reduced libido or slower recovery
- want to record a baseline of their hormones
- have already done a testosterone test and want to complete the picture
When it comes to men's hormones, SHBG is almost always looked at together with testosterone so a doctor can place the values in context.
What is tested?
This test measures one biomarker in your blood:
- SHBG (sex hormone-binding globulin): a protein that binds sex hormones, in particular testosterone.
Because SHBG helps estimate how much free testosterone you have, it is best reviewed together with a testosterone test. You can read more on the page about SHBG (sex hormone-binding globulin).
What can this test tell you?
Your SHBG says something about how much of your testosterone is bound and therefore not directly available. A high SHBG may lower your amount of free testosterone, even when your total testosterone looks normal.
That is why SHBG is hard to interpret on its own. Only together with your testosterone does a picture emerge that a doctor can use to place your symptoms.
How is the sample collected?
For this test, blood is drawn at a certified sample point. There are 700+ locations across the Netherlands, which you choose yourself after ordering.
You do not need to see your GP first. You pick a location and a time that suit you, and the draw by trained staff usually takes only a few minutes.
When is this test useful?
SHBG is especially useful when your testosterone tells you something, but your symptoms do not quite seem to match. The value can then explain why your amount of free testosterone is higher or lower than your total testosterone suggests.
Because testosterone is usually highest in the morning, blood for this combination is generally drawn in the morning.
What do the results mean?
Your result shows your SHBG alongside a reference range and a short explanation. What counts as a healthy value varies by lab, age and person, so a single number says little on its own.
A high or low SHBG value can affect how much usable testosterone you have. Only a doctor can properly interpret your value together with your testosterone and your symptoms.
Preparation
For SHBG you usually do not need to fast. If you want the value assessed together with testosterone, a blood draw in the morning is often advised, when testosterone is usually highest.
If you use medication or hormones, ask your doctor whether that could affect your result.
What happens after the results?
Your results are available online within a few working days. You see your SHBG value, its reference range and a clear explanation.
Every blood test result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
Frequently Asked Questions
From order to report in 4 steps
No referral needed. No waiting list. Just order and go.
Choose your blood test
Pick a testosterone check, hormone panel, or prostate screening. Or build a custom test with exactly the markers you want.
Receive your lab referral
On the same business day you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician assesses your results and writes a personal report. On your dashboard within a few business days.
Choose your blood test
Pick a testosterone check, hormone panel, or prostate screening. Or build a custom test with exactly the markers you want.
Receive your lab referral
On the same business day you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician assesses your results and writes a personal report. On your dashboard within a few business days.
Always a location near you
With 700+ certified phlebotomy points across the Netherlands.
What We Test
This panel includes 1 biomarkers, each tested at a certified laboratory using medical-grade equipment.
Sex hormone-binding globulin (SHBG) is a protein produced by the liver that binds to sex hormones, including testosterone and estrogen. It helps regulate the amount of free, active hormones available in the body.
Learn moreSHBG (Sex Hormone Binding Globulin)
HormonesSex hormone-binding globulin (SHBG) is a protein produced by the liver that binds to sex hormones, including testosterone and estrogen. It helps regulate the amount of free, active hormones available in the body.
SHBG levels may help explain symptoms related to hormone imbalances even when total hormone levels appear normal. Understanding SHBG can provide a more complete picture of hormonal health. Consult your healthcare provider to interpret results.
Related biomarkers
Biomarkers often explored alongside this test for a fuller picture.
17-OH Progesterone
17-OH Progesterone is a precursor steroid hormone essential for producing cortisol and androgens like testosterone. For men, monitoring this marker may provide insight into adrenal function and androgen production pathways.
ACTH (Adrenocorticotropic Hormone)
ACTH is a pituitary hormone that directs your adrenal glands to produce cortisol. For men, ACTH levels may reflect how your body handles physical and mental stress, directly influencing energy and hormonal balance.
Androstenedione
Androstenedione is a key precursor hormone that your body converts into testosterone. For men, monitoring this marker may offer direct insight into your testosterone production pathway and overall androgenic hormone balance.
Calcitonin
Calcitonin is a thyroid hormone that helps regulate calcium and bone metabolism. For men, monitoring calcitonin may provide insight into thyroid C-cell health and calcium balance, supporting a complete picture of your hormonal status.
Cortisol
Cortisol is the primary stress hormone that influences energy, metabolism, and recovery. For men, chronic elevation may affect testosterone production and body composition.
DHEA-S
DHEA-S is an adrenal androgen precursor that supports testosterone production. Monitoring helps men assess adrenal reserve and age-related hormonal decline.
Related Tests
Explore more tests that might interest you.
Cortisol Test
We advise against this test for stress, burnout or fatigue. Order it only if your doctor asked for it.
DHEA-S Test
Measure your DHEA-S, an adrenal building block for your sex hormones. No referral needed.
Testosterone Test
Measure your testosterone, the main male hormone for energy, muscle and libido. No referral needed.
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