DHEA-S is an adrenal androgen precursor that supports testosterone production. Monitoring helps men assess adrenal reserve and age-related hormonal decline.
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| Sex | Age | Reference range (umol/l) | Relative scale |
|---|---|---|---|
| Male | · 21–30 years | 1–14,2 umol/l |
1
14,2
|
| Male | · 31–40 years | 0,9–11,3 umol/l |
0,9
11,3
|
| Male | · 41–50 years | 0,4–10,6 umol/l |
0,4
10,6
|
| Male | · 51–60 years | < 8,1 umol/l |
8,1
|
| Male | · 61–70 years | < 6,8 umol/l |
6,8
|
| Male | · 71–80 years | < 5,6 umol/l |
5,6
|
| Male | · 81–90 years | < 2,9 umol/l |
2,9
|
Reference values per age decade and sex, as published in the lab guide of Maastricht UMC+. For the bands published as "< value" (women from 41 years, men from 51 years) the source gives no lower limit: a low result therefore gets no verdict, because the source says nothing about it. DHEA-S falls sharply with age and does not depend on the menstrual cycle. There are no bands below 21 or above 90 years. Note: laboratories and measurement methods differ considerably in the reference values they use for DHEA-S, in both the lower and the upper limits. So always go by the reference value on your own result.
Source: Maastricht UMC+, Centraal Diagnostisch Laboratorium Reference population: MUMC+ lab guide (Maastricht UMC+, DHEA-S reference values)
Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.
Check your own valueThis test measures the blood concentration of DHEA-S, the sulfated storage form of DHEA. Because DHEA-S levels remain stable throughout the day, it is a reliable indicator of adrenal androgen production.
Declining DHEA-S may contribute to reduced vitality, lower testosterone, and decreased muscle mass in men. Tracking levels supports proactive hormonal health management. Consult your healthcare provider.
Testing may be recommended when evaluating adrenal function, investigating symptoms of androgen excess or deficiency, or assessing age-related hormonal decline.
Some people may experience chronic fatigue, decreased libido, reduced muscle mass, or low mood when DHEA-S levels are below the expected range. These symptoms could suggest adrenal depletion.
Some people may experience acne, oily skin, excessive hair growth, or hair thinning when DHEA-S levels are elevated. In women, this could suggest an androgen-related hormonal imbalance.
Low DHEA-S may indicate adrenal insufficiency or aging. Consider adrenal function testing and lifestyle optimization.
Elevated DHEA-S may indicate adrenal tumors or PCOS. Consult with an endocrinologist for evaluation.
Adequate sleep, regular moderate exercise, and effective stress management may support healthy DHEA-S production. Avoiding chronic overtraining and ensuring sufficient recovery time could also be beneficial. Discuss supplementation only with your healthcare provider.
Yes, DHEA-S peaks in early adulthood and declines steadily. Your healthcare provider can assess whether your level is appropriate for your age.
DHEA-S is the sulfated storage form of DHEA, with more stable blood levels. It is preferred for testing because it does not fluctuate throughout the day.
DHEA supplements are available but should only be used under medical supervision, as they can affect other hormone levels. Consult your healthcare provider first.
This marker is included in the following test panels.
Measure your DHEA-S, an adrenal building block for your sex hormones. No referral needed.
Articles that explain this value in context.
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Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
DHEA-S
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