Cortisol is the primary stress hormone that influences energy, metabolism, and recovery. For men, chronic elevation may affect testosterone production and body composition.
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We advise against this test
We advise against measuring cortisol if your question is about stress, burnout, fatigue or weight gain. Cortisol fluctuates so much that your value has to roughly double before any change is detectable, and the contraceptive pill, pregnancy, night shifts and even the stress of the blood draw itself shift the result. If your doctor requested this measurement, have your blood drawn between 06:00 and 10:00 in the morning. Read why we advise against this test.
Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.
Check your own valueThis test measures the concentration of cortisol in your blood, reflecting adrenal gland function and your body's current stress response. Morning samples provide the most clinically meaningful results.
Elevated cortisol may suppress testosterone and promote abdominal fat storage. Monitoring helps men identify stress-related hormonal imbalances early. Consult your healthcare provider.
Pause biotin
RequiredDo you take a supplement with biotin (vitamin B8, common in hair, skin and nail supplements)? Stop it 72 hours before the draw. Biotin interferes with the measurement of these values.
Have the draw in the morning
RequiredThese values vary over the day and peak in the morning. Have your blood drawn before 10:00, ideally between 07:00 and 09:00.
Testing may be recommended when experiencing symptoms of chronic stress, fatigue, unexplained weight changes, or sleep disturbances. Morning blood draws provide the most reliable baseline measurement.
Some people may experience persistent fatigue, dizziness, muscle weakness, or unexplained weight loss when cortisol levels are low. These symptoms could suggest adrenal insufficiency and warrant medical evaluation.
Some people may experience weight gain around the midsection, difficulty sleeping, elevated blood pressure, or mood changes when cortisol levels are persistently elevated. Discuss these symptoms with your healthcare provider.
Low cortisol may indicate adrenal insufficiency. Seek immediate medical attention if experiencing fatigue, weakness, or low blood pressure.
High cortisol may indicate Cushing's syndrome, chronic stress, or depression. Consider stress management, sleep optimization, and endocrine evaluation.
Regular physical activity, consistent sleep schedules, and stress management techniques such as mindfulness or breathing exercises may help support healthy cortisol patterns. Reducing caffeine intake in the afternoon could also be beneficial.
Morning blood draws are preferred, as cortisol peaks shortly after waking. Your healthcare provider can advise on optimal timing.
Yes, acute stress or anxiety before the test may temporarily elevate cortisol. Try to remain calm before your blood draw.
Chronic stress, certain medications, and adrenal conditions may contribute. Your healthcare provider can help determine the underlying cause.
This marker is included in the following test panels.
We advise against this test for stress, burnout or fatigue. Order it only if your doctor asked for it.
Articles that explain this value in context.
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Medical policyDoctor's Assessment Included
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
Cortisol
€29,-
